Biochemistry and Molecular Biophysics

BMB/Bi/Ch 170. Principles of Three-Dimensional Protein Structure. 9 units (3-3-3); first term. Prerequisite: Bi/Ch 110. The forces determining the folding of proteins into their unique tertiary structures. Protein structures will be classified by organization of the structural elements and structural motifs, and their influence on function will be explored. Topics will include enzyme and antibody structure and function, virus structures, protein–nucleic acid interactions, methods of macromolecular structure determination, and protein structure analysis. A computer graphics system will be used for the display and analysis of macromolecular structure. Instructors: Bjorkman, Rees.

BMB/Bi/Ch 174. Biophysical Chemistry. 9 units (3-0-6); second term. Prerequisite: BMB/Bi/Ch 170. Principles of biophysical chemistry and structural biological techniques such as protein folding, structure prediction, NMR spectroscopy, various forms of protein imaging, and design. Instructors: Jensen, Mayo.

Bi/BMB 251 abc. Current Research in Cellular and Molecular Biology. 1 unit. For course description, see Biology.

BMB 278. Fundamentals of Molecular Genetics. 9 units (3-0-6); third term. Prerequisite: BMB 176. Principles and mechanisms of DNA repair and replication, transcription and splicing, and protein synthesis. Instructors: Campbell, Parker.

BMB 299. Graduate Research. Units to be arranged; first, second, third terms. Students may register for research units after consultation with their adviser.