BIOCHEMISTRY AND MOLECULAR BIOPHYSICS

BMB/Bi/Ch 170 abc. Biochemistry and Biophysics of Macromolecules and Molecular Assemblies. 9 units (3-1-5); first, second, third terms. Prerequisite: Bi/Ch 110. First term: detailed analysis of the structures of the four classes of biological molecules and the forces that shape them. Introduction to molecular biological and visualization techniques. Energetic principles and molecular mechanism of enzymatic catalysis. Practical kinetic techniques. Second term: basic principles of modern biophysical and structural methods to interrogate macromolecules from the atomic to cellular levels, including X-ray crystallography, NMR spectroscopy, molecular dynamics, electron and light microscopy, AFM, single molecule techniques, and systems biological simulations. Third term: detailed analysis of specific macromolecular machines and systems that illustrate the principles and biophysical methods taught in the first two terms. Instructors: Clemons, Jensen, Shan, staff.

Bi/BMB 251 abc. Current Research in Cellular and Molecular Biology. 1 unit. For course description, see Biology.

BMB 278. Fundamentals of Molecular Genetics. 9 units (3-0-6); third term. Principles and mechanisms of DNA repair and replication, transcription and splicing, and protein synthesis. Not offered 2009–10.

BMB 299. Graduate Research. Units to be arranged; first, second, third terms. Students may register for research units after consultation with their adviser.