Varmus to speak at commencement

Harold Varmus, the chief executive officer of Memorial Sloan-Kettering Cancer Center and the former director of the National Institutes of Health, will be the principal speaker at Caltech’s 109th commencement ceremonies, which will take place on Friday, June 13, 2003.

“Harold Varmus is a great speaker, great educator, great administrator and a great research scientist,” said Caltech president David Baltimore. “As the head of a cancer institute and the former head of the National Institutes of Health, he understands and can illuminate the research-and-development environment in which many of our graduates will make their lives.”

Varmus is a corecipient of the 1989 Nobel Prize in physiology or medicine, awarded for research that demonstrated the cellular origins of the oncogene of a chicken retrovirus. This discovery contributed to an understanding of cell growth in human cancer. Oncogenes are normal genes that control cell growth; under certain circumstances, they mutate and direct the cell to grow at a fierce pace. The research done by Varmus and corecipient J. Michael Bishop has improved the diagnosis and treatment of a variety of cancers.

A graduate of Amherst College, Harvard University, and Columbia University’s College of Physicians and Surgeons, Varmus was a faculty member at UC San Francisco for 23 years. It was there that he and Bishop performed much of their research.

In 1993, Varmus was appointed by then-president Bill Clinton to serve as director of the National Institutes of Health. Under his watch, the NIH underwent dramatic growth. He held that post until 1999 and took over the top post at Sloan-Kettering at the beginning of the following year.

In addition to his Nobel Prize–winning work, Varmus also does research on the replication cycles of retroviruses and hepatitis B viruses. The author of four books and 300 scientific papers, he has served as an advisor to pharmaceutical and biotechnology firms, academic institutions, and the U.S. government. Currently, Varmus lends his knowledge to the World Health Organization’s macroeconomics and health commission and to a National Research Council panel on genetically modified organisms, and works on the development of mouse models for human cancer.